SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c0a8a213b96770fabb54826e7c112df92a3b1626f27bfd72c612dd471c5d15' 
  AND token = 'eIcfhtpxRuWFskwtJNoWY54JzHivVVbGz6I7UF9dly8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}