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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6e7c5dc1207c8f17249828f3c9ac7870010838f2be58756de9409608eb11c1e' 
  AND token = 'rQKIhh/6+fpbwrd6Bu4mVrYUmYZibuOUyfNEMVELZQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}