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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6739462a271403a8853b9d1153a6de957bda7d561fb57d9a76e671d334e5c9a2' 
  AND token = 'sjm9YG3B4hrPkIU4I4mpM7EAyoN0ojyetDr2bb87vWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}