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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '369dc9ac4c9aa33cfc23a06f4e8425f906bdcc3032ec39f1b784778fc648e78c' 
  AND token = 's8NIHGPGLbftFwbruKJS9sJAeZm6HXevfhE4oQxdI/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}