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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72001d273f2b6428db121828100cc3333db15f66ca0257294973a063a1a42b02' 
  AND token = '+sOqOxAmG6ilmAAUE71DKUjWYhrU4yvv43t3mvVef7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}