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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f4f591597ef2abd6f0503f7461689b74f217c46755002f12d2de0c105047fb3' 
  AND token = 'Y3R0LC2/DpiUkZzqfSoZrXdKR0LeL0nCFQaMPJ+l2S0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}