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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de3053522cfd378bf91680fe65d2b0df6f03954adca6b4d223ec62ecdd8f691' 
  AND token = 'hcpK4V4oGMh5UZt4Z2kFkhIeYng6ptat6uEN1T96xbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}