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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '846efc6e852cd089347ed28709f2b7b49f38baae1fa1213409de121827a446df' 
  AND token = 'lG/d0TDBi3n+fYm/WITmqbuXKNLzn6gtCexHQWAI4U0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}