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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '733027c6d13ee12561fd5a3ad64e5b609576b6a6cf425e84bb17188508b5a04a' 
  AND token = 'ETHv00Lplzfcc6dPgeWiM48s6W8R06Bb0SvI/Le+V3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}