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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f10bc3945092fa2360ec1c6c224bdfeeb2ac8307e484d6814263978bd320b295' 
  AND token = 'Ive0jbh9UNzsiQpyzeikIM+/Kfk/0/eSpECpV7gAmYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}