SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d784e979a2893b0784c1fa579834febea504bd54fcfaa60f282491d3669e85c' 
  AND token = 'F5Hk/4lONlMLQDvAWkU8rjmPE+I3VW9b2VXfITlGCl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}