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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '739158ec4fc674184795f3fc096878e63b6a59937a6226c223d1ce1700bcd8b1' 
  AND token = 'D81tfaOiRdT5LqAh91YFdg09wu1aN1pFD5tMPkr1Z3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}