SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eb74c94b8032de19dd283a0852b982e4e3443a3c0dddb13dcd60bab0bf2c8ee' 
  AND token = 'ihMS1k3BAlrZji7TUI1OdCmTs7ZZ9/ezs/vlur+d/Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}