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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5182f76ee8437bee3171b32d431277800ab23b42b9abd2e17cf69ee388ed7b51' 
  AND token = 'H+ZEu0afLjzlJLMcgUWRVt+ZX9sbEZmoqCa4QFNKJi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}