SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a81ca4bf24f42795602f1302c3efc167adc4391035725e376fe3b57395ff4c06' 
  AND token = 'HZOn7eE2pG+IVGjGes+4wrT+hVjCzvu1pADz92Ar0vA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}