SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e361ba922f9419a4e3563ce4488fcba5b3122173e20f60b4e4d471e78998a7' 
  AND token = 'XZVCw6IKLtl9LSjB5WlspskCdSBKXNVmt+gfHbJoERU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}