SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4162cb9fd43d803264481bfe405c1e1deadbd344b4ea99c9f54e6ca95777ebd1' 
  AND token = 'yjEk8Jc/FmQIvyiSXR/IzYuzKbmOwi6SHfPsLPgNh34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}