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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52173539c8ac374d49f6145bacdd4b108447730d9a3f18711d1db1d894f69c3' 
  AND token = 'ZV28fUU5nMMucS132KPBuUoCY1PPf0hC+2dOtPRS2hE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}