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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53ae086a2075b43269d65c59435b69af8c61170494ec470c7ab266bca1b7e794' 
  AND token = 'vAPL07fofQ6zfmexsViOSL4l+aioAKQu7CFW8p/g5mY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}