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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87249e8dc6f651d75647f039221c1f2c8fe495c6d9e42465bb7c67274bc12e1d' 
  AND token = '/TixH93PXCFX2VIeNeewxBGHBamk8A9HUknnRKeyGI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}