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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9640fd7dc4413c6f3bae9d16e07a62cedd5f96d233c37115f71307b1385e5b59' 
  AND token = 'W0+OU5F4FWRrA7MTlqKbGbQHY2b9bVcOPq+2qhV+7I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}