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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6233686640320acbc3ae8cd2a0f70e36f14d94228ea407b7c76f3b33577f306' 
  AND token = 'oPQniirQHEDM4Aiuc1d44C3toEK70/znHsBVV9vjwhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}