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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4ee0e36d24dfaff1259f3735a82124219fa04127ba63b3efa2a4262228904ce' 
  AND token = '45hmRZXa1y6VS8RsUQK69zMvuARJsnxF81quPOGgd6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}