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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59c3d9d3e4c26d7115ea275fbf2f9cb0ea11cfd1bb54e8d82bc1fda751738655' 
  AND token = '8x21KbLnV4HgZbIGlee5F/sl3SheJyURfv4f7D6sLGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}