SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d2dc5f4c3cd4d33ebea774eb84515700373d9e5dcab6d4a1d71de3298019728' 
  AND token = '1ejj5pGm+VuVESbTx6J/1AU0Neptejn1deHRrn17k10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}