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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0625c3d174b137436486af3f71e80a7d80c398b6027d0c049324b7d92de8300' 
  AND token = '5Ham38I36H5G6M9SilbfZvinkSDziYVwENtjK/3i2II=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}