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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e289ca365a2ee13013c88eba38f660b1f9f733de4ecf9230ed34f027f066c1e0' 
  AND token = 'dEBp3Tlurros55txTwHgB7YJrMW6a2Hu2RW9XGVVre8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}