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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f896fc5d232846908fc0d3d47b3a1ad55541d01d5e174b1bd67a702196d817' 
  AND token = 'yU2U1P2TS8k10q8X2kSZR4F/0YN2m4OH3uKjvIc5KQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}