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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d3bffd096e787fd6427ca8f2df4401eef0295bf0ea5aa1422d6db1b3ee5100' 
  AND token = 'M3yc8PmoD731WHDpAp6J0BrcmtFRJJQeBfm1zAD0wmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}