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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3897f26310bd97017b112d90e971361cfdd5ce5358ea658b2ab43b2ebe41e7' 
  AND token = 'RgUybx5+OdltA3xUgF0N66X4WhyZOpsMPVr4kpAE1R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}