SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4b75f5f29599ec4d2ca0f52cad51caf346c9718da4220248b4b9bd71b31f46b' 
  AND token = '8v/X1Hsi10zEC3XurulvhBnBCIotB3zxewdxW06aHhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}