SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b9b3cc988080fe9f6fdcd6030b7d72ac33be19b0f110a095a0f479a1a51786' 
  AND token = 'NyfOjfEoeDEv1W1oCpILeuP2aTVqlFNfOAFzq8spSYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}