SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10260fc4e50bbe5562663606fe66e5beed9708de4d4f13df21645a40a04fbbe5' 
  AND token = '39MPxkLFlQM5XiMPcVeDM9DpMHCly/0ge0BnCZEom5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}