SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f430a33978798171178f0585603e76f2fd3d75def75cb580640bee406b166e38' 
  AND token = 'pDGRX0ZpqNerOe6k2+71vXKGM3UC41fEqCBTu/K9YVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}