SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0eafe1ba901bf16743ae8c2c7b85f3a845e74903f810a4f7af972cbb41731ab' 
  AND token = 'pAv9+Xck9VWmCthz925QWAQF4ZUwjT/4ECZu+tgWjl4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}