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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bbe5c8b7c55d6087244247ff3ec783ac72bb406518c37f20f4d134590aae1a' 
  AND token = '16WNCtAJiSMm0QatdWIxI3EVApsNMm+eZ7SjdiwDJiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}