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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc43f749389cf45cfd0339361050505a30c2802c4e3b7907ff33fc18d26a3472' 
  AND token = '3LgjOcpKG1VS8t8TTWbUzcSi8uELbwy9oXP/MrGzaDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}