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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a0367376434c8ee8de6e04174950c0141a80e889b1d2d1253b539d481b1c32' 
  AND token = 'L9eleLjiQXjwVEgnSvqWwMgFwNd+RsnIDbBgBhaIvPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}