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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b79626bcdab56740a86dc92b03525042d31e1b1d0c19bad03a9c4f3c07ed97' 
  AND token = 'FfvpGGS+8sbh5/Q9q/LYOmtofDKEx4va4T4Bpht+tRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}