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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1bc6c3969aa26492a8368b2c55e0050143eb3516bf6b7e304c804b7fdf1c791' 
  AND token = 'fsKl+ceoShMv6J7H8m/mm4fqwc27v0HMRvS2B+lgfwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}