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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cac3d217d607cad8affd8b1b9d1cd7d218ca31cb3a9e547c501489a1a0c55366' 
  AND token = '5TDlYHwldmkhRCa6nRU6SlnBBJ4hKU09TS6JEwUTon4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}