SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e65f35c17b6553cbd445359069e03e1591123d4f3647fca1817d7acc3ca5b89' 
  AND token = 'M3462Qrb00J4ywZbip9hmezyvguNSugOyFTsryU0WRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}