SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c9a773f484577d42664b6db64deb2a385aa5b254ad308c58182e7f37efdde8' 
  AND token = 'vUrVVLyYZtZpEndnUvhmXxTGQakmFSNXcT0bUBTrLWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}