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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71a9768960f4da79e61b1782849bd26322b12428c14e5da5e573032127f26624' 
  AND token = 'deMtw/d1gFE/3fATu7IvU0HVav56iv0Bu5pSOYy6NYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}