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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b3218a3a12596f9f15e09caf8deed6f66ff8769ceee7e7758db9f9005a4496' 
  AND token = 'Yxii20d9Z2JYN9QdFqX7fJC4g5lEOB0U2JMRX7O5WZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}