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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3131368cf32aa6b78e5fbdaeadfb4db6e727500937df7b2f7f0d3b103223c828' 
  AND token = 'jQEcruRM6xknF98QzErFyuIVEo4waJ03K3tY8CHMiDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}