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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8de724fe94e5effcd039ad8154c0a58c4945352cf6a00cc4e17009f873d3b231' 
  AND token = '2QU4DK2dZ3Iu/tY7Ab1H/8w3mEWBWAtD+98W46+azhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}