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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4b672947bb650dded432c1b5c04f44840491c626794a0c1201970f9eef93375' 
  AND token = '0cM2k6qPXpjEuRK107dQTkHhRWGH2GbJg6dVNHcjezA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}