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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def26d6381cf433aeccf8ccba3380c5732cefc193650f9ed12f3d3582418e9e3' 
  AND token = 'ORPj38CYhB8cg3EAtz5bFb2hc/3VBHlvublYcmbpqLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}