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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab0eccb787d11cb7031ed664b0684059cc9dfe264275eb961ebe643b7343ba7c' 
  AND token = 'o2i2Jc6OxUJVDtI25sOmxt7ZrwFKN94smuA4Ux4zVng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}